Enantioselective Synthesis of a 9,10-seco-Taxane Derivative via Electrophilic Epoxy-allylsilane Ring Closure

DOI: 10.1039/c39930001823

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1823 - 1825 (1993)

Update date:2022-08-03

Topics:

Authors:

Pettersson, Lars

Frejd, Torbjoern

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c39930001823

seco-Taxane 8, a potential starting material for further development into highly substituted taxanes, is synthesized by BF3*OEt2 treatment of epoxy-allylsilane 7, in its turn synthesized by joining an A-ring derivative 2 with a C-ring precursor chain 3.

Full text of DOI:10.1039/c39930001823

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:(1R,3S,5S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-formyl-3-hydroxy-2,2-dimethyl-6-methylene-cyclohexanecarboxylic acid ethyl ester

Cas No:136611-34-2

R&D Labs maybe for 136611-34-2

Jiaxing Barton Chemicals

website:http://www.chinabarton.com

Contact:+86-573-82719618

Address:No. 162 Fumin Road, Honghe Town,
Taizhou Huading Chemical Co.,Ltd(expird)

Contact:+86-576-88583898

Address:Economic&Technology development zone,Taizhou City,Zhejiang Province,China
Xinji City Taida Sinopec Co., Ltd.

Contact:0086-311-85341278

Address:No.6, Nanhua Road,Xinji City Road,Hebei Province,China
Jiangsu King Road New Materials Co., Ltd.

website:http://www.jskingroad.com

Contact:0519-85720726 0519-85720721 15006126856

Address:No.1,Weihua Road,Xinbei District,Changzhou City,Jiangsu Province
Huaihua Baohua Biotechnology Co.,Ltd

website:http://www.baochengchem.com

Contact:86-519-82698291

Address:HouYang chemical development zone,Jintan,Jiangsu,China (213200)

Relevant to this article

Synthesis, characterization, and electrochemical properties of benzyloxy-functionalized diiron 1,3-propanedithiolate complexes relevant to the active site of [FeFe]-hydrogenases

Doi:10.1021/om300136b
(2012)
The Pictet-Spengler reaction of N(b)-hydroxytryptamines and cysteinals. II. Temperature effects, stereochemistry and mechanism

Doi:10.1248/cpb.39.1672
(1991)
Pyrene-fluorene hybrids containing acetylene linkage as color-tunable emitting materials for organic light-emitting diodes

Doi:10.1021/jo300285v
(2012)
A non-metal catalysed oxidation of primary azides to nitriles at ambient temperature

Doi:10.1039/c2ob06949k
(2012)
Discovery of an 8-aza-5-thiaProstaglandin E₁ analog as a highly selective EP4 receptor agonist

Doi:10.1248/cpb.59.1494
(2011)
Doi:10.1021/jo01037a068
(1963)

Article Doi