Synthesis of 5-azaspiro[2.4]heptan and penta-substituted pyrrole derivatives via pd-catalyzed intramolecular cyclization reaction of alkynyl carboxamides

Article abstract of DOI:10.1080/00397911.2010.535944

Penta-substituted pyrrole derivatives, including a three-membered ring (5-azaspir-o[2.4]heptan), were readily prepared in moderate to excellent yields by the Pd-catalyzed intramolecular cyclization reaction of alkynyl carboxamide compounds. When an excess