Synthesis of 3-amino-6-dimethylamino-4-oxopyrazolo[3,4-d][1,3]oxazine derivatives

Article abstract of DOI:10.1055/s-1991-26538

3-Amino-1-aryl-6-dimethylamino-4-oxo-1,4-dihydropyrazolo[3,4- d][1,3]oxazines 4a-7a and 3-amino-2-aryl-6-dimethylamino-4-oxo-2,4-dihydropyrazolo[3,4- d][1,3]oxazines 4b-6b were synthesized from 4-chloro-5-cyano-2-dimethylamino-6-oxo-6H-1,3-oxazine 2 and arylhydrazines in good yields. The substituent effect of the arylhydrazines on the yields of products was clearly observed.