Tetrahedron p. 3915 - 3924 (1991)
Update date:2022-09-26
Topics:
Hensens
Wichmann
Liesch
VanMiddlesworth
Wilson
Schwartz
The structures and absolute stereochemistry of restriction (1), its N,N-dimethyl derivative (4) and desglycyl hydrolysis product (3), isolated from Penicillium restrictum, have been determined on the basis of spectroscopic evidence. They belong to a new class of broad spectrum antifungal agents representing substituted tetrahydropyranyl ethers incorporating triene and glycyl ester side chains.
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Doi:10.1016/S0040-4039(00)73573-8
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