Diastereoselective Claisen Condensation-Type Reactions of Alkyl 2,2-dialkoxycyclopropanecarboxylates with Esters and Acid Chlorides Promoted by Titanium(IV) Chloride

DOI: 10.1246/cl.1991.1475

Source and publish data:

Chemistry Letters p. 1475 - 1478 (1991)

Update date:2022-09-26

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Authors:

Shimada, Shigeru

Saigo, Kazuhiko

Hashimoto, Yukihiko

Maekawa, Yasunari

Yamashita, Takashi

et al. et al.

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Article abstract of DOI:10.1246/cl.1991.1475

In the presence of titanium(IV) chloride, alkyl 2,2-dialkoxycyclopropanecarboxylates reacted with esters and acid chlorides to give Claisen condensation-type products.The reaction essentially proceeded with extremely high diastereoselectivity.

Full text of DOI:10.1246/cl.1991.1475

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