Total synthesis of (-)-nupharamine and (+)-3-epinupharamine via asymmetric nitroso Diels-Alder reaction

Article abstract of DOI:10.1016/S0040-4039(00)92161-0

Chiral synthesis of (-)-nupharamine and (+)-3-epinupharamine, based on elaboration of the intramolecular asymmetric Diels-Alder reaction of N-acylnitroso compounds and the introduction of the furyl group in a fully stereocontrolled manner, is described.