Tetrahedron p. 6265 - 6274 (1991)
Update date:2022-08-05
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Fadel
Cyclopropanone acetal 2a undergoes the one-pot Strecker synthesis under sonication to provide the amino nitrile 8, which after hydrolysis and catalytic hydrogenolysis, gives 1-aminocyclopropanecarboxylic acid (ACC, 1) in good overall yield.
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