Tetrahedron p. 3945 - 3960 (1992)
Update date:2022-08-03
Topics: Cyclization Stereoselective Pyrrolidines Radical-mediated Enantiopure Transition state
Belvisi, Laura
Gennari, Cesare
Poli, Giovanni
Scolastico, Carlo
Salom, Barbara
Vassallo, Marco
Radical-mediated cyclization of norephedrine derived α-iodoamides 1 was found to be highly stereoselective (<*> 97:3) favouring diastereoisomer 2.Bicyclic lactams 2 were transformed in high yields into enantiomerically pure pyrrolidines 10.Transition stat
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