Synthesis of (+)-dihydrocompactin and (+)-compactin via vinylsilane terminated cationic cyclization

Article abstract of DOI:10.1016/S0040-4039(00)92272-X

Two enantioselective routes to the octalin diol 1 are described, featuring cationic polyene cyclization mediated by a vinylsilane terminating group and a benzenedimethanol acetal initiator. Further transformations resulting in formal and total syntheses o