Journal of the Chemical Society. Chemical communications p. 1289 - 1290 (1991)
Update date:2022-08-05
Topics: Chemical formula Reagent Organic synthesis Introduction Experiment Moiety
Chen, Chen
Crich, David
In the presence of metallic zinc 3-bromopropyne reacts with aldehydes to give homopropynylic alcohols which are converted to the corresponding bromohomopropynylic acetates by acetylation followed by reaction with N-bromosuccinimide and a catalytic quantity of silver acetate; these derivatives are then oxidized to γ-acetoxy-α-ketoesters with osmium tetroxide and tert-butyl hydroperoxide resulting in a convenient four step sequence for the introduction of the pyruvate moiety.
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Doi:10.1016/j.tet.2012.03.091
(2012)Doi:10.1016/j.ejmech.2012.02.024
(2012)Doi:10.1246/bcsj.65.385
(1992)Doi:10.1016/j.bmcl.2012.04.015
(2012)Doi:10.1002/chem.201100229
(2012)Doi:10.1021/jo00025a031
(1991)
