A Practical and Efficient Method for the Construction of the Biphenyl Framework; Nucleophilic Aromatic Substitution on 2-Methoxybenzoates with Aryl Grignard Reagents

DOI: 10.1039/c39910001375

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1375 - 1376 (1991)

Update date:2022-08-05

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Authors:

Hattori, Tetsutaro

Suzuki, Takatsugu

Miyano, Sotaro

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Article abstract of DOI:10.1039/c39910001375

Treatment of 2-methoxybenzoic esters derived from 2,6-dialkylphenols with aryl Grignard reagents afforded 1,1'-biphenyl-2-carboxylates in excellent yields.

Full text of DOI:10.1039/c39910001375

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