SESQUITERPENOIDS FROM THE LIVERWORT BAZZANIA JAPONICA

Article abstract of DOI:10.1016/S0031-9422(00)98247-5

Two new tetracyclic sesquiterpenoids, cyclomyltaylan-3-ol and its caffeate, have been isolated from the stem-leafy liverwort Bazzania japonica together with the previously known five sesquiterpenoids and their absolute stereostructures established by a combination of the 1H and 13C NMR spectral data as well as X-ray crystallographic analysis and CD spectrum.Bazzania japonica is divided into two chemo-types, cyclomyltaylane-type and cuparene-drimane-type.Cyclomyltaylyl-3-caffeate inhibited release of superoxide anions at IC 50 7.5 μg ml^-1.Key Word Index - Bazzania japonica; Jungermanniales; Hepaticae; cyclomyltaylan-3-ol; cyclomyltaylyl-3-caffeate; 2-hydroxycuparene; albicanol; albicanyl acetate; albicanyl caffeate; isobicyclogermacrenal; sesquiterpenoids; superoxide release inhibitory activity; chemosystematics.