Synthetic Communications p. 2694 - 2706 (2012)
Update date:2022-08-05
Topics:
Worth, Anna C.
Needham, Catherine E.
Franklin, Donald B.
Lampkins, Andrew J.
(Chemical Equation Presented) Novel 4-alkoxy-dithionaphthoic acids were prepared and shown to be valuable synthons for δ-amino acid conjugates. These dithioacids are efficiently synthesized and purified, stable to storage, and easily derivatized to facilitate thioacylation chemistry. To this end, we have demonstrated dithionaphthoic acids (6) to successfully undergo coupling with both protected and unprotected amino acids, giving rise to stable thioamide conjugates (8 and 9). Copyright Taylor & Francis Group, LLC.
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Doi:10.1002/ejoc.201200068
(2012)Doi:10.1021/jo401169z
(2013)Doi:10.1002/ejoc.201101725
(2012)Doi:10.3762/bjoc.16.15
(2020)Doi:10.1016/S0040-4039(00)79453-6
(1991)Doi:10.1002/chem.201103624
(2012)