A specific molecular beacon probe for the detection of human prostate cancer cells

DOI: 10.1016/j.bmcl.2012.04.055

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 3632 - 3638 (2012)

Update date:2022-08-02

Topics:

Authors:

Jiang, Yu Lin

McGoldrick, Christopher A.

Yin, Deling

Zhao, Jing

Patel, Vini

Brannon, Marianne F.

Lightner, Janet W.

Krishnan, Koyamangalath

Stone, William L.

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Article abstract of DOI:10.1016/j.bmcl.2012.04.055

The small-molecule, water-soluble molecular beacon probe 1 is hydrolyzed by the lysate and living cells of human prostate cancer cell lines (LNCaP), resulting in strong green fluorescence. In contrast, probe 1 does not undergo significant hydrolysis in ei

Full text of DOI:10.1016/j.bmcl.2012.04.055

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