Chemical conversion of vitamin D3 to its 1,25-dihydroxy metabolite

DOI: 10.1016/0040-4039(91)80752-R

Source and publish data:

Tetrahedron Letters p. 6057 - 6060 (1991)

Update date:2022-08-03

Topics:

Authors:

Kiegiel Kiegiel

Wovkulich

Uskokovic

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Article abstract of DOI:10.1016/0040-4039(91)80752-R

Vitamin D₃ (6) has been converted to the 1,25-dihydroxy vitamin D₃ metabolite (1) and the 1α-fluoro derivative 2 via a new process. The strategy involved the cleavage of the ring A portion from the CD portion in vitamin D₃

Full text of DOI:10.1016/0040-4039(91)80752-R

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