Zwitterion formation and subsequent carboxylate-pyridinium NH synthon generation through isomerization of 2-anilinonicotinic acid

DOI: 10.1039/c8ce01255e

Source and publish data:

CrystEngComm p. 6126 - 6132 (2018)

Update date:2022-09-26

Topics:

Authors:

Yue, Pengyun

Dong, Caiqiao

Zhang, Mingtao

Xu, Danrui

Parkin, Sean

Li, Tonglei

Li, Conggang

Yu, Faquan

Long, Sihui

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Article abstract of DOI:10.1039/c8ce01255e

Through structural modification of 2-anilinonicotinic acid by isomerization, the ΔpK_a between the carboxylic acid and pyridinium NH increased dramatically over the threshold to form zwitterions in the newly designed 4-anilinonicotinic acids. Th

Full text of DOI:10.1039/c8ce01255e

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