Tetrahedron Letters p. 6633 - 6636 (1991)
Update date:2022-08-04
Topics:
Roos, Eric C.
Bernabe, Pablo
Hiemstra, Henk
Speckamp, W. Nico
When the Pd(0)-catalyzed hydrostannolysis of the N-allyloxycarbonyl group is carried out in the presence of an activated carbonyl compound, a coupling product is formed.This new method appears to be applicable to the synthesis of a wide range of amides and peptides.Key Words: allyloxycarbonyl, palladium(0), amides, peptide coupling, amino acids
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