Antiestrogens. 3. Estrogen Receptor Affinities and Antiproliferative Effects in MCF-7 Cells of Phenolic Analogues of Trioxifene, phenyl>methanone

DOI: 10.1021/jm00083a019

Source and publish data:

Journal of Medicinal Chemistry p. 931 - 938 (1992)

Update date:2022-07-30

Topics:

Authors:

Jones, Charles D.

Blaszczak, Larry C.

Goettel, Mary E.

Suarez, Tulio

Crowell, Thomas A.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00083a019

Benzothiophenes 3 and 4, derived from the acrylophenone antiestrogen trioxifene (2), are characterized by high estrogen receptor (ER) affinity and low residual estrogenicity compared to tamoxifen (1a).In order to characterize further the growth supperessi

Full text of DOI:10.1021/jm00083a019

Products guided by the article

Product name:Methanone, (3,4-dihydro-2-hydroxy-6-methoxy-1-naphthalenyl)(4-methoxyphenyl)-

Cas No:138630-68-9

R&D Labs maybe for 138630-68-9

Shanghai Dynamic Industrial Co.,Ltd.

website:http://www.shdynamic.com

Contact:86-021 3392 6680

Address:Room 805 Information Tower, No.1403 Minsheng Road, Pudong New Area, Shanghai 200135, P. R. China
Chengdu Cogon Bio-tech Co., Ltd.

Contact:86-28-85171192

Address:NO.52.YongFeng Rd. Chengdu,610041,P.R.China.
HuiFeiChem PharmaTech Co.Ltd

Contact:0510-85393305

Address:1619 Huishan Avenue, Huishan District, Wuxi,
Hangzhou Ocean Chemical Co., Ltd.

website:http://www.hzoceanchem.com

Contact:+86-571-88025872, 28272092, 28272096

Address:Room 623 ,Building No 1 , COFCO Radius Commercial Center Xiwen Road, Xiacheng District, Hangzhou, Zhejiang Province, China
Shanghai Sinofluoro Scientific Co., Ltd

Contact:+86-21-64279360

Address:Room 1006,Building 3,#58 East Xinjian Road, Shanghai ,201100,China,

Relevant to this article

Conjugate addition-aldol approach to the simple bicyclic-diynene core structure found in the esperamicins and calicheamicins

Doi:10.1016/S0040-4039(00)91637-X
(1992)
Research on African medicinal plants. XXVII. Interjectin, a derivative of nyasicoside from Hypoxic interjecta and Hypoxis multiceps

Doi:10.1016/S0040-4020(01)82323-1
(1991)
An efficient and diastereoselective [2+2] cycloaddition: Convenient and enantioselective route to trans-2',3'-dihydroxymethylcyclobutane nucleoside analogs

Doi:10.1016/0040-4039(91)85023-X
(1991)
Carbocycles from Carbohydrates. A Free Radical Route to (1R,2R,3S,4R)-4-Amino-1,2,3-cyclopentanetriol Derivatives

Doi:10.1016/S0957-4166(00)86136-4
(1991)
Synthesis of (-)-δ-N-Normethylskytanthine

Doi:10.1016/0040-4039(91)80484-N
(1991)
The Diastereoselective Formation of 1,2,4-Trioxanes and 1,3-Dioxolanes by the Reaction of Endoperoxides with Chiral Cyclohexanones

Doi:10.1002/hlca.19970800813
(1997)

Article Doi