Antiestrogens. 3. Estrogen Receptor Affinities and Antiproliferative Effects in MCF-7 Cells of Phenolic Analogues of Trioxifene, phenyl>methanone

DOI: 10.1021/jm00083a019

Source and publish data:

Journal of Medicinal Chemistry p. 931 - 938 (1992)

Update date:2022-07-30

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Authors:

Jones, Charles D.

Blaszczak, Larry C.

Goettel, Mary E.

Suarez, Tulio

Crowell, Thomas A.

et al. et al.

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Article abstract of DOI:10.1021/jm00083a019

Benzothiophenes 3 and 4, derived from the acrylophenone antiestrogen trioxifene (2), are characterized by high estrogen receptor (ER) affinity and low residual estrogenicity compared to tamoxifen (1a).In order to characterize further the growth supperessi

Full text of DOI:10.1021/jm00083a019

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