Cyclocondensation of α-oxoketene N,S-acetals with β-lithioamino-β-substituted acrylonitriles: A facile route to 2,6-substituted 4-amino-3-cyanopyridines

Article abstract of DOI:10.1055/s-1991-26602

A novel synthesis of a variety of 2,6-substituted and 3-cyano-4-dialkylamino-2,6-diheteroarylpyridines (4-dialkylamino≡pyrrolidin-1-yl, piperidino, morpholino, diethylamino and N-methylanilino; 6-heteroaryl≡phenyl, anisyl, 2-thienyl; 2-heteroaryl≡methyl,