Structure and synthesis of a new butanolide from a marine actinomycete

Article abstract of DOI:10.1016/0040-4039(91)85024-Y

The novel butanolide 2, (1′R, 2S, 4S)-2-(1-hydroxy-6-methylheptyl)-4-hydroxymethyl-butanolide, was isolated from the culture broth of a marine actinomycete. The structure of 2 was assigned by analysis of spectral data and the absolute configuration was determined by synthesis.