Tetrahedron p. 10065 - 10076 (1991)
Update date:2022-08-05
Topics:
Meerpoel, Lieven
Toppet, Suzanne M.
Compernolle, Frans
Hoornaert, Georges J.
An approach to the synthesis of acyclo-1-deazathymidine nucleosides is described. Diels-Alder reaction of 3,5-dichloro-6-methyl-2H-1,4-oxazin-2-one with acetylenic compounds 4 and 5 yielded the 3-[(tetrahydropyran-2-yl)oxy]-methyl- and 3-bromomethyl-5-met
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