Triazolo[4,5-d]pyrimidines. XI. Halogen-metal exchange reaction of 5-halo-3H-1,2,3-triazolo-[4,5-d]pyrimidines with butyllithium

DOI: 10.1248/cpb.39.3037

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 3037 - 3040 (1991)

Update date:2022-08-05

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Authors:

Tanji Tanji

Kato Kato

Higashino

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Article abstract of DOI:10.1248/cpb.39.3037

The amino group at the 5-position on the 3H-1,2,3-triazolo[4,5-d]pyrimidine (triazolopyrimidine) ring was converted into a halogen atom by treatment with isopentyl nitrite in halomethanes in satisfactory yields. The 5-halotriazolopyrimidines not having a

Full text of DOI:10.1248/cpb.39.3037

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