Synthesis of 6-Phosphonoalkyl Tetrahydro-4-pyrimidinecarboxylic Acids as NMDA Receptor Antagonists

DOI: 10.1016/0040-4039(91)80558-N

Source and publish data:

Tetrahedron Letters p. 7659 - 7662 (1991)

Update date:2022-08-03

Topics:

Authors:

Bigge, Christopher F.

Wu, Jiang-Ping

Drummond, James R.

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Article abstract of DOI:10.1016/0040-4039(91)80558-N

The title compounds were prepared via a sequence which involved as the key steps a Michael reaction between nitroalkyl phosphonates and protected dehydroalanine and subsequent cyclization of the α,γ-diamino esters.Key Words: 6-phosphonoalkyl tetrahydro-4-

Full text of DOI:10.1016/0040-4039(91)80558-N

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