Formation of Peptide Thioamides by Use of Fmoc Amino Monothioacids and by PyBOP

DOI: 10.1016/0040-4039(91)80549-L

Source and publish data:

Tetrahedron Letters p. 7617 - 7620 (1991)

Update date:2022-09-26

Topics:

Authors:

Hoeg-Jensen, Thomas

Jakobsen, Mogens Havsteen

Olsen, Carl Erik

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Article abstract of DOI:10.1016/0040-4039(91)80549-L

Endothiopeptides have been obtained by using PyBOP<*> promoted coupling between Fmoc-protected amino monothioacids and amino acid or peptide esters.The protected endothiopeptides (Fmoc-Gly-Φ(CSNH)-Phe-OEt, Fmoc-Tyr(Bu^t)-Φ(CSNH)-Gly-Gly-Phe-Leu-

Full text of DOI:10.1016/0040-4039(91)80549-L

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