Journal of Medicinal Chemistry p. 1692 - 1699 (1991)
Update date:2022-08-04
Topics:
Kroona, Heather B.
Peterson, Nancy L.
Koerner, James F.
Johnson, Rodney L.
The cyclopropyl compounds (Z)- and (E)-2-amino-2,3-methano-4-phosphonobutanoic acid, 5 and 6, respectively, were prepared as constrained analogues of 2-amino-4-phosphonobutanoic acid (AP4), a selective glutamate receptor ligand.A Horner-Emmons reaction of
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