Tetrahedron Letters p. 17 - 20 (1992)
Update date:2022-08-03
Topics:
Georg, Gunda U.
Guan, Xiangming
α-Alkylated azocane-2-carboxylic acid methyl esters 5 were synthesized with excellent enantiomeric excess (>96%) in four steps starting from optically active β-keto esters 1. The synthesis involved tetrazole formation, reduction, protection, and oxidation
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