Stereo-Modulating Catalysis by Europium(III) Complexes in Aldol Reactions of Chiral α-Alkoxy Aldehydes with Ketene Silyl Acetals

Article abstract of DOI:10.1246/cl.1992.29

The Eu(fod)3- or Eu(dppm)3-catalyzed aldol reactions of the four chiral α-alkoxy aldehydes having different protecting groups with (E)- or (Z)-ketene silyl acetals are shown to provide the high levels of diasterocontrol, the sense depending on the nature