
Tetrahedron Letters p. 273 - 276 (1992)
Update date:2022-08-03
Topics: Yield NMR spectroscopy Synthetic route Chromatography Purification
Malpass, John R.
Smith, Craig
1,4-Functionalisation of cycloocta-1,3-diene using a nitroso-cycloaddition strategy is followed by intramolecular cyclisation to yield 9-azabicyclo<4.2.1>nonanes (homotropanes) and -non-7-enes (homotrop-7-enes); the approach can be adapted to allow access
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