Microbial approach to chiral 2-thiazolyl γ- and δ lactones

DOI: 10.1016/S0957-4166(00)82317-4

Source and publish data:

Tetrahedron Asymmetry p. 107 - 114 (1992)

Update date:2022-07-31

Topics:

Authors:

Fantin Fantin

Fogagnolo

Medici Medici

Pedrini Pedrini

Poli Poli

Gardini Gardini

Guerzoni

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Article abstract of DOI:10.1016/S0957-4166(00)82317-4

The synthesis of chiral 2-thiazolyl γ- and δ-lactones 6 and 7 via microbial reduction of the appropriate keto esters to the homochiral hydroxy esters followed by chemical lactonization is described. Some attempts of enzymatic lactonization of the racemic

Full text of DOI:10.1016/S0957-4166(00)82317-4

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