Journal of the Chemical Society. Perkin transactions II p. 1855 - 1858 (1985)
Update date:2022-08-04
Topics:
Srinivasan, Chockalingam
Perumal, Subbu
Arumugam, Natesan
The kinetics of oxidation of some ortho-substituted N,N-dimethylanilines by peroxodisulphate have been studied in 50percent (v/v) aqueous ethanol containing 0.025 mol/dm3 phosphate buffer (pH 7).The reaction is second-order overall, and first-order in each reactant.The rate is not influenced by the presence of free-radical inhibitor allyl acetate.An increase in the polarity of the medium enhances the rate.The reactivities of ortho-substituted anilines lie in the order o-H > Me ca.MeO > F > Br > Cl > NO2.Multiple regression analysis of the rate data reveals that the rate is susceptible to significant electronic and steric effects.All these observations are rationalised on the basis of attack of the oxidant at the ipso-position of the amine.Correlation analysis of reactivity data from the literature also indicates that the mechanism involves ipso-attack and not attack on nitrogen.
View MoreXi'an Galaxy Chemicals CO., Ltd
Contact:86-29-89380370
Address:No.8, Gaoxin three road, Xi'an city.
TIANJIN NORTH JINHENG CHEMICAL PLANT.
Contact:0086-22-59952083
Address:DongShigu Country In JiXian TianJin China
jiangsu senxuan pharmaceutical and chemical co.,ltd
Contact:86-523-87982810
Address:hongqiao industrial zone,taixing,jiangsu china
Zhengzhou Xinlian Chemical Tech Co. ,Ltd
Contact:0371-65771781 021-52042910
Address:H Part, Building I, No. 700 Gonglu Road, Pudong New Area, Shanghai
shanghai meicheng chemical co .,ltd(expird)
Contact:+86-21-50677091
Address:Room 302, Building 7, No.1000, Jinhai Road
Doi:10.1021/ja304602t
(2012)Doi:10.1039/c2cc35004a
(2012)Doi:10.1039/c2dt30446e
(2012)Doi:10.1126/science.aao0270
(2017)Doi:10.1016/j.ejmech.2012.07.013
(2012)Doi:10.1039/c8nj04867c
(2018)
