
Journal of Medicinal Chemistry p. 1791 - 1799 (1992)
Update date:2022-08-02
Topics: Antagonists
Salituro, Francesco G.
Harrison, Boyd L.
Baron, Bruce M.
Nyce, Philip L.
Stewart, Kenneth T.
et al.
A series of substituted 3-(2-carboxyindol-3-yl)propionic acids was synthesized and tested as antagonists for the strychnine-insensitive glycine binding site of the NMDA receptor.Chlorine, and other small electron-withdrawing substituents in the 4- and 6-p
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