Addition of Amino Amides to Vinyl Vicinal Tricarbonyls. Formation of Tricyclic 3-Azadethiacephams

DOI: 10.1021/jo00035a019

Source and publish data:

Journal of Organic Chemistry p. 2641 - 2645 (1992)

Update date:2022-08-05

Topics:

Authors:

Wasserman, Harry H.

Henke, Susan L.

Nakanishi, Eiji

Schulte, Gayle

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00035a019

Amino amides react as trinucleophiles with vinyl vicinal tricarbonyl esters.Reaction of the primary amino group takes place at the β-position of the α,β-unsaturated ketone along with addition to the central carbonyl group.In a third-stage reaction, the am

Full text of DOI:10.1021/jo00035a019

Products guided by the article

Product name:7-<1-<1-<(tert-butyldimethylsilyl)oxy>ethyl>>-6-methyl-9a-carbobenzoxy-1,8-dioxoazetidino<1,2-c>perhydropyrrolo<1,2-a>pyrimidine

Cas No:139976-61-7

R&D Labs maybe for 139976-61-7

Zhaodu Fine Chemical Plant

Contact:86-310-8067016

Address:East Fuhua Road,Tiexi Chemical Industrial Estate,Hebei,China
HANGZHOU TOYOND BIOTECH CO., LTD

Contact:+86-571-86965177

Address:No. 189, Fengqi East Road, Hangzhou, China
Exploiter Molybdenum Co.,Ltd

Contact:86-379-63338609

Address:Jiudian Village,Deting Town,Song County,Luoyang
Zhengzhou Minzhong Pharmaceutical Co.,ltd

Contact:0086-371-65797115

Address:15/F,Jiangshan Bldg, NO.126 Huanghe Road,Zhengzhou, China
Nanjing Habo Medical Technology Co., Ltd.

Contact:025－85769882

Address:No.108. Ganjiabian east. Qixia District .Nanjing

Relevant to this article

Highly efficient and selective deprotection method for prenyl, geranyl, and phytyl ethers and esters using borontrifluoride-etherate

Doi:10.1080/00397911.2011.589561
(2013)
Hydrogen bonding directed intermolecular cope-type hydroamination of alkenes

Doi:10.1021/ol3023177
(2012)
Catalytic asymmetric claisen rearrangement of enolphosphonates: Construction of vicinal tertiary and all-carbon quaternary centers

Doi:10.1002/anie.201203092
(2012)
1,3-Bis(trimethylsilyl)propene as 1,3- and 3,3-Propene Dianion Synthons. Reactions of 2-Aryl-1,3-bis(trimethylsilyl)propenes with Electrophiles

Doi:10.1021/jo00035a046
(1992)
Silicon acceleration of a tandem alkene isomerization/electrocyclic ring-opening of 2-methyleneoxetanes to α,β-unsaturated methylketones

Doi:10.1021/jo4014645
(2013)
An efficient synthesis of thiazolidine-4-ones with antitumor and antioxidant activities

Doi:10.1002/jhe.641
(2012)

Article Doi