Synthesis and protective effect of 1,3,5-triazine derivatives, leukotriene C4 antagonist, on HCl·ethanol-induced gastric lesions in rats

DOI: 10.1248/cpb.39.3180

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 3180 - 3182 (1991)

Update date:2022-08-03

Topics:

Authors:

Hasegawa

Yanagisawa

Okui Okui

Sato Sato

Hosaka Hosaka

Chin Chin

Mitsuhashi

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Article abstract of DOI:10.1248/cpb.39.3180

2,4-Diamino-[E]-6-[2-(3-pyridyl)ethenyl]-1,3,5-triazine (3a), leukotriene C₄ (LTC₄) antagonist, was found to possess a protective effect on HCl·ethanol-induced gastric lesions. Analogues of 3a were synthesized and evaluated for the e

Full text of DOI:10.1248/cpb.39.3180

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