Ring-opening Reactions of N-Aryl-1,2,3,4-tetrahydroisoquinoline Derivatives

Article abstract of DOI:10.1016/S0040-4020(01)88133-3

The reaction of N-nitroaryl-1,2,3,4-tetrahydroisoquinolines 1a-e, 1g and 1j with N-bromosuccinimide (NBS) afforded aldehydes 3a-e, 3h and 3j respectively.N-(4-Nitrophenyl)-1-phenyl-1,2,3,4-tetrahydroisoquinoline 1n gave ketone 3n together with brominated product 3o when treated with NBS.