Studies on uricosuric diuretics. III. Substituted 1,3-dioxolo[4,5-f]-1,2-benzisoxazole-6-carboxylic acids and 1,3-dioxolo[4,5-g]-1,2-benzisoxazole-7-carboxylic acids

DOI: 10.1248/cpb.40.109

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 109 - 116 (1992)

Update date:2022-08-04

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Authors:

Sato Sato

Dan Dan

Onuma Onuma

Tanaka Tanaka

Aoki Aoki

Koga Koga

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Article abstract of DOI:10.1248/cpb.40.109

A series of substituted 1,3-dioxolo[4,5-f]-1,2-benzisoxazole-6-carboxylic acids 13 and 1,3-dioxolo[4,5-g]-1,2benzisoxazole-7-carboxylic acids 14 were synthesized and evaluated for diuretic and uricosuric activities in rats. Most of the benzisoxazole deriv

Full text of DOI:10.1248/cpb.40.109

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