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General Method for the Synthesis of 2'-Azido-2',3'-dideoxynucleosides by the Use of -Hydride Shift and &β-Elimination Reactions

DOI: 10.1039/P19920000469

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 469 - 478 (1992)

Update date:2022-08-04

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Authors:

Kawana, MasajiroKawana, Masajiro

Kuzuhara, HiroyoshiKuzuhara, Hiroyoshi

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Article abstract of DOI:10.1039/P19920000469

The title nucleoside (16U, C, G and H) were synthesized from pyrimidine and purine ribonucleosides in about 30percent overall yield in 6 steps via key intermediates, protected 3'-deoxy-arabino-nucleosides, which were obtained by deoxygenative <1,2>-hydrid

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