Facile unmasking of ethenylated isocytosines via diacetoxylation with lead tetraacetate

DOI: 10.1248/cpb.40.235

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 235 - 237 (1992)

Update date:2022-08-04

Topics:

Authors:

Sako Sako

Totani Totani

Hirota Hirota

Maki Maki

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.40.235

Treatment of ethenylated isocytosines, imidazolo[1,2-a]pyrimidine-5(1H)-one (2) and -7(8H)-one (3), with lead tetraacetate (LTA) in glacial acetic acid followed by alkaline hydrolysis resulted in the smooth removal of the ethenyl group to give isocytosine (1) in high yields. The unmasking of 2 by LTA to 1 was compared with the results using iodosylbenzene diacetate and N-bromosuccinimide.

Full text of DOI:10.1248/cpb.40.235

NII-Electronic Library Service

Products guided by the article

Product name:Imidazo[1,2-a]pyrimidin-5(1H)-one, 6-bromo-

Cas No:140685-72-9

R&D Labs maybe for 140685-72-9

Huzhou City Linghu Xinwang Chemical Co.,Ltd.

Contact:86-572-3948695/3945236

Address:huzhou
HangZhou HuaYe Chemical Technology Co.,Ltd

Contact:+86-13505815007

Address:hangzhou
Jiangxi Biochem Co.,Ltd

Contact:86-791-86629460

Address:1-6F, 118 Xinzhou road, Nanchang, Jiangxi, China
NANCHANG QINZHI SCI&TEC.CO.,LTD(expird)

Contact:+86-13687004106

Address:Hero South Road,Hero Zone,Nanchang,Jiangxi,China
Zouping Mingxing Chemical Co.,Ltd.

website:http://www.zoutong.com.cn

Contact:86-543-2240068 2240067

Address:428 Daixi Third Road Zouping County Shandong Province China

Relevant to this article

ACETALS OF ACID LACTAMS AND AMIDES. 70. REACTIONS OF 2-AMINOMETHYLENEINDOLIN-3-ONE WITH CH-ACIDS. SYNTHESIS OF SUBSTITUTED PYRROLO<1,2-a>INDOLES

Doi:10.1007/BF00484358
(1991)
Synthesis and structural characterization of highly fluorinated sulfimides and sulfoximides as functional building blocks for materials science

Doi:10.1002/ejoc.200400702
(2005)
Silyl-based alkyne-modifying linker for the preparation of C-terminal acetylene-derivatized protected peptides

Doi:10.1021/jo302305d
(2012)
Improved Ca_v2.2 channel inhibitors through a gem -dimethylsulfone bioisostere replacement of a labile sulfonamide

Doi:10.1021/ml4002612
(2013)
Insertion reactions and catalytic hydrophosphination of heterocumulenes using α-metalated N, N-dimethylbenzylamine rare-earth-metal complexes

Doi:10.1021/om300807k
(2013)
RECYCLIZATION REACTIONS OF SMALL RINGS. 8. SYNTHESIS OF 5-SUBSTITUTED 2-OXAZOLIDONES FROM THIAZOLIDINE-2,4-DIONE AND OXIRANES

Doi:10.1007/BF00472300
(1991)

Article Doi