
Chemical and Pharmaceutical Bulletin p. 235 - 237 (1992)
Update date:2022-08-04
Topics:
Sako
Totani
Hirota
Maki
Treatment of ethenylated isocytosines, imidazolo[1,2-a]pyrimidine-5(1H)-one (2) and -7(8H)-one (3), with lead tetraacetate (LTA) in glacial acetic acid followed by alkaline hydrolysis resulted in the smooth removal of the ethenyl group to give isocytosine (1) in high yields. The unmasking of 2 by LTA to 1 was compared with the results using iodosylbenzene diacetate and N-bromosuccinimide.
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Doi:10.1007/BF00484358
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(1991)