Journal of Organic Chemistry p. 3906 - 3916 (1992)
Update date:2022-08-05
Topics: Diastereoselectivity Column chromatography Yield NMR spectroscopy Nucleophile Electrophile Enantiomeric excess (ee) Deprotonation Imine Enantioselective synthesis HPLC (high-performance liquid chromatography) Catalytic asymmetric synthesis Stereocontrol Condensation Reaction β-Lactam Chiral Auxiliary Schiff Base Enolate Alkylation ester enolate
Steen, Fred H. van der
Kleijn, Henk
Britovsek, George J. P.
Jastrzebski, Johann T. B. H.
Koten, Gerard van
Three approaches to the enantioselective synthesis of 3-amino-4-substituted-2-azetidinones by condensation of α-amino ester enolates with imines are described: (i) application of chiral ester derivatives of N,N-diethylglycine; (ii) application of chiral N
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