Asymmetric Construction of Quaternary Carbons from Chiral Malonates: Selective and Versatile Total Syntheses of the Enantiomers of α- and β-Cuparenones from a Common Optically Active Precursor

DOI: 10.1021/jo00038a041

Source and publish data:

Journal of Organic Chemistry p. 3463 - 3473 (1992)

Update date:2022-07-29

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Authors:

Canet, Jean-Louis

Fadel, Antoine

Salauen, Jacques

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Article abstract of DOI:10.1021/jo00038a041

From a single chiron (R)-4, available with high enantiomeric purity (96percent) by simple enzymatic hydrolysis (PLE) of a prochiral malonate, were prepared convenient precursors of the two enantiomers of α- and β-cuparenones (1a,b and 2a,b).This versatile

Full text of DOI:10.1021/jo00038a041

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