Synthesis of 2'-C-cyano-2'-deoxy- And 2'-C-cyano-2',3'-dideoxy-β-D-arabinofuranosyl Nucleosides

Article abstract of DOI:10.1016/S0040-4020(01)88727-5

A series of 2'-C-cyano-2'-deoxy- and 2'-C-cyano-2',3'-dideoxy arabinofuranosyl nucleosides have been prepared by reaction of the corresponding 2'-ulosyl- and 3'-deoxy-2'-ulosyl nucleosides with sodium cyanide followed by 2'-deoxygenation of the cyanohydri