
Tetrahedron Letters p. 1577 - 1580 (1992)
Update date:2022-08-02
Topics:
Baker, William R.
Condon, Stephen L.
The nonpeptide renin inhibitor, A-68064, and the ACE inhibitor methyl enalaprilat were synthesized from (5S)-2,3,5,6-tetrahydro-5-benzyl(butyl)-N-(tert-butoxycarbonyl)-4H-1,4-oxazine-2-ones 7a and 7b, and (5S)-2,3,5,6-tetrahydro-5-methyl-N-(tert-butoxycarbonyl)-4H-1,4-oxazine-2-one 12, respectively.Key words: nonpeptide renin inhibitor; ACE inhibitor.
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Doi:10.1021/jo00038a036
(1992)Doi:10.1021/ja309085b
(2012)Doi:10.1021/acs.joc.5b02273
(2015)Doi:10.1007/s00706-012-0867-5
(2012)Doi:10.1016/j.bmcl.2012.09.047
(2012)Doi:10.1016/j.ica.2012.08.003
(2013)