New route to 2-substituted indoles by pyrolysis of N-acylacetylphenylhydroxylamines

DOI: 10.1016/S0040-4039(00)91646-0

Source and publish data:

Tetrahedron Letters p. 1459 - 1462 (1992)

Update date:2022-07-30

Topics:

Authors:

Hirao Hirao

Mohri Mohri

Yonemitsu

Tabata Tabata

Sohma Sohma

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Article abstract of DOI:10.1016/S0040-4039(00)91646-0

Convenient and regiospecific synthesis of 2-substituted indol (3) by thermolysis of N-acylacetylphenylhydroxylamine (1) and its mechanism including the formation of a radical intermediate are reported.

Full text of DOI:10.1016/S0040-4039(00)91646-0

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