Fluorescent nitrile-based inhibitors of cysteine cathepsins

DOI: 10.1016/j.bmcl.2012.09.086

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 7715 - 7718 (2012)

Update date:2022-08-05

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Authors:

Frizler, Maxim

Mertens, Matthias D.

Gütschow, Michael

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Article abstract of DOI:10.1016/j.bmcl.2012.09.086

Cysteine cathepsins play an important role in many (patho)physiological conditions. Among them, cathepsins L, S, K and B are subjects of several drug discovery programs. Besides their role as drug targets, cysteine cathepsins are additionally considered t

Full text of DOI:10.1016/j.bmcl.2012.09.086

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