Synthesis and biological activities of N-(3-Carboxylpropyl)-5-amino-2- hydroxy-3-tridecyl-1,4-benzoquinone and analogues

DOI: 10.1021/np3007099

Source and publish data:

Journal of Natural Products p. 2209 - 2215 (2012)

Update date:2022-08-04

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Authors:

Madathil, Manikandadas M.

Khdour, Omar M.

Jaruvangsanti, Jennifer

Hecht, Sidney M.

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Article abstract of DOI:10.1021/np3007099

The synthesis of benzoquinone natural product 2 and three analogues is described. The synthesized compounds were tested for their ability to protect Friedreich's ataxia (FRDA) lymphocytes from induced oxidative stress. One of the analogues (3) conferred c

Full text of DOI:10.1021/np3007099

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