Synthesis and biological evaluation of new oral carbapenems with 1-methyl-5-oxopyrrolidin-3-ylthio moiety

DOI: 10.7164/antibiotics.52.900

Source and publish data:

Journal of Antibiotics p. 900 - 907 (1999)

Update date:2022-08-04

Topics:

Authors:

Kanno, Osamu

Miyauchi, Masao

Shibayama, Takahiro

Ohya, Satoshi

Kawamoto, Isao

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Article abstract of DOI:10.7164/antibiotics.52.900

The synthesis and biological properties of 1β-methylcarbapenems with 1-methyl-5-oxopyrrolidin-3-ylthio group at the C-2 position were studied. The sodium (1R,5S,6S)-6-[(R)-1-hydroxyethyl]-1-methyl-2-[(R)-1-methyl-5-oxopyrrolidin-3 -ylthio]-1-carbapen-2-em

Full text of DOI:10.7164/antibiotics.52.900

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Product name:(S)-4-hydroxy-1-methyl-2-oxopyrrolidine

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