Tetrahedron Letters p. 15 - 20 (2013)
Update date:2022-08-03
Topics:
Schmink, Jason R.
Tudge, Matthew T.
A palladium-catalyzed cross coupling of nitrogen bearing heterocyclic chloromethyl derivatives with aryl and heteroaryl boronic acids has been developed. In almost all cases, highly efficient cross-couplings were observed at ambient temperature, mitigating unwanted thermally induced side-reactions. The comprehensive substrate scope and respectable yields highlight the synthetic utility of this reaction.
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Doi:10.1007/s00044-012-0400-8
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(2013)
