Renin inhibitors. I. Synthesis and structure-activity relationship of transition-state inhibitors containing homostatine analogues at the scissile bond

DOI: 10.1248/cpb.40.364

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 364 - 370 (1992)

Update date:2022-08-04

Topics:

Authors:

Atsuumi Atsuumi

Nakano Nakano

Koike Koike

Tanake Tanake

Matsuyama

Nakano Nakano

Morishima

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.40.364

The synthesis and structure-activity relationships of transition-state renin inhibitors containing the homostatine analogues at the scissile bond are described. These inhibitors incorporate the amino acid side chains corresponding to positions 7-12 (P View More

Full text of DOI:10.1248/cpb.40.364

NII-Electronic Library Service

Products guided by the article

Product name:(2R,3S)-3-Azido-2-benzyloxy-4-cyclohexyl-butyraldehyde

Cas No:141713-86-2

R&D Labs maybe for 141713-86-2

Zhengzhou Institute of Chiral Pharmer Research Co., Ltd.

Contact:86-371-55219111

Address:15 Floor, 2 Building, Central China Technovalley, Zhongyuan West Road
Wuhan Kemi-Works Chemical Co., Ltd

website:http://www.kemiworks.com

Contact:86-27-85736489

Address:Rm. 1503, No. 164, Jianghan North Rd., Wuhan, 430022 China
Changzhou Kingyo Chemical Corporation Ltd.

website:http://www.kingyochem.com

Contact:+86-519-85105717

Address:19# Wuqing North Road, Changzhou , Jiangsu, China
GenicBio Limited

Contact:+86-(0)21-3770 9035

Address:Room 301, Building 2, Meijiabang Road 1508, Shanghai China
Shanghai Longjin Metallic Material Co., Ltd.

website:http://www.shlongjin.cn/

Contact:021-56517503,56502257

Address:No.16, Lane 555, Chengyin Road, Shanghai

Relevant to this article

Aeruginazole A, a novel thiazole-containing cyclopeptide from the cyanobacterium microcystis sp.

Doi:10.1021/ol1014015
(2010)
An efficient method for phosphorylation of alcohols: Preparation of porphyrin-derived phosphates

Doi:10.1055/s-0032-1317344
(2012)
Gold-catalysed tuning of reactivity in allenes: 9-endo hydroarylation versus formal 5-exo hydroalkylation

Doi:10.1039/c2cc37872h
(2013)
Enantioselective Construction of Spiro Quaternary Carbon Stereocenters via Pd-Catalyzed Intramolecular α-Arylation

Doi:10.1021/acs.orglett.0c01129
(2020)
Design, synthesis, and structure–activity relationship studies of the anaephene antibiotics

Doi:10.1111/cbdd.13903
(2021)
Self-assembly of 5,11,17,23-tetranitro-25,26,27,28-tetramethoxythiacalix[4] arene with neutral molecules and its use for anion recognition

Doi:10.1016/j.tet.2012.10.101
(2013)

Article Doi