Renin inhibitors. I. Synthesis and structure-activity relationship of transition-state inhibitors containing homostatine analogues at the scissile bond

DOI: 10.1248/cpb.40.364

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 364 - 370 (1992)

Update date:2022-08-04

Topics:

Authors:

Atsuumi Atsuumi

Nakano Nakano

Koike Koike

Tanake Tanake

Matsuyama

Nakano Nakano

Morishima

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Article abstract of DOI:10.1248/cpb.40.364

The synthesis and structure-activity relationships of transition-state renin inhibitors containing the homostatine analogues at the scissile bond are described. These inhibitors incorporate the amino acid side chains corresponding to positions 7-12 (P View More

Full text of DOI:10.1248/cpb.40.364

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