Organic Process Research and Development p. 646 - 651 (2015)
Update date:2022-07-30
Topics:
Boiteau, Jean-Guy
Rodeville, Nicolas
Martin, Cédric
Tabet, Samuel
Moureou, Christine
Muller, Franck
Jetha, Jean-Claude
Cardinaud, Isabelle
Herein, we report the kilogram-scale synthesis of CD08108, a novel MC1R agonist. This synthesis has been developed to produce the first batches of this compound for preclinical and clinical studies. Two amido couplings were used to synthesize the backbone
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