Asymmetric Synthesis. 26. An Expeditious Enantioselective Synthesis of the Defense Alkaloids (-)-Euphococcinine and (-)-Adaline via the CN(R,S) Method

DOI: 10.1021/jo00041a028

Source and publish data:

Journal of Organic Chemistry p. 4211 - 4214 (1992)

Update date:2022-08-03

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Authors:

Yue, Chongwei

Royer, Jacques

Husson, Henri-Philippe

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Article abstract of DOI:10.1021/jo00041a028

The unnatural enantiomer (-)-euphococcinine (2) and the natural enantiomer of (-)-adaline (3), two homotropane alkaloids, were each prepared in three steps from chiral (-)-2-cyano-6-oxazolopiperidine synthon 8 by the CN(R,S) method.The key steps of these

Full text of DOI:10.1021/jo00041a028

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