Synthesis of 2-Phenyl-, 3-Phenyl-, cis-2,3-Diphenyl-, and trans-2,3-Diphenyl-1,4-thiazanes and Derivatives (N-Methyl, N-Alkoxycarbonyl, S-Oxides, and S,S-Dioxides)

Article abstract of DOI:10.1021/jo00041a029

The syntheses of the title 1,4-thiazanes (thiamorpholines) by reduction of the 5-oxa-1,4-thiazanes resulting from the lactamization of the appropriate acyclic phenyl derivatives of 5-amino-3-thiapentanoic acid are reported.The oxidation reactions at sulfu